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Afsar B, Afsar RE (2023) Sodium-glucose cotransporter inhibitors and kidney fibrosis: review of the current evidence and related mechanisms

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The increase in cAMP levels in -cells is a consequence of GLP-1R activation in these cells, which in turn enhances the secretion of growth inhibitory hormone through signaling pathways such as PKA and Calcium/Calmodulin-dependent protein kinase (Strowski et al., 2000

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